FocusCell Biomechanics

ROCK in a Stiff Place

Science Translational Medicine  07 Dec 2011:
Vol. 3, Issue 112, pp. 112fs12
DOI: 10.1126/scitranslmed.3003389

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Abstract

Understanding the molecular and cellular mechanisms involved in the progression of atherosclerosis has revealed a vital role for the Rho kinase (ROCK) pathway associated with stiffening of the underlying extracellular matrix (Huynh et al., this issue).

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