Research ArticleObesity

A Peptidomimetic Targeting White Fat Causes Weight Loss and Improved Insulin Resistance in Obese Monkeys

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Science Translational Medicine  09 Nov 2011:
Vol. 3, Issue 108, pp. 108ra112
DOI: 10.1126/scitranslmed.3002621

Article Information

vol. 3 no. 108 108ra112

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication May 5, 2011
  • Accepted for publication October 21, 2011

Author Information

  1. Kirstin F. Barnhart1,2,
  2. Dawn R. Christianson1,3,
  3. Patrick W. Hanley2,
  4. Wouter H. P. Driessen1,3,
  5. Bruce J. Bernacky2,
  6. Wallace B. Baze2,
  7. Sijin Wen4,
  8. Mei Tian5,
  9. Jingfei Ma6,
  10. Mikhail G. Kolonin7,
  11. Pradip K. Saha8,9,
  12. Kim-Anh Do4,
  13. James F. Hulvat10,
  14. Juri G. Gelovani5,
  15. Lawrence Chan8,9,
  16. Wadih Arap1,3,5,*, and
  17. Renata Pasqualini1,3,5,*,
  1. 1David H. Koch Center, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  2. 2Department of Veterinary Science and Keeling Center for Comparative Medicine and Research, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  3. 3Department of Genitourinary Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  4. 4Department of Biostatistics, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  5. 5Department of Experimental Diagnostic Imaging, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  6. 6Department of Imaging Physics, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  7. 7Brown Foundation Institute of Molecular Medicine for the Prevention of Human Disease, University of Texas Health Science Center, Houston, TX 77030, USA.
  8. 8Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  9. 9Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  10. 10Ablaris Therapeutics, Pasadena, CA 91101, USA.
  1. *To whom correspondence should be addressed. E-mail: rpasqual{at}mdanderson.org (R.P.); warap{at}mdanderson.org (W.A.)

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