PerspectiveBioengineering

From DNA to Targeted Therapeutics: Bringing Synthetic Biology to the Clinic

Science Translational Medicine  26 Oct 2011:
Vol. 3, Issue 106, pp. 106ps42
DOI: 10.1126/scitranslmed.3002944

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Abstract

Synthetic biology aims to make biological engineering more scalable and predictable, lowering the cost and facilitating the translation of synthetic biological systems to practical applications. Increasingly sophisticated, rationally designed synthetic systems that are capable of complex functions pave the way to translational applications, including disease diagnostics and targeted therapeutics. Here, we provide an overview of recent developments in synthetic biology in the context of translational research and discuss challenges at the interface between synthetic biology and clinical medicine.

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