Meeting ReportsSchizophrenia

Translational Neuroscience of Schizophrenia: Seeking a Meeting of Minds Between Mouse and Man

  1. Martien J. Kas1,*,
  2. René S. Kahn2,
  3. David A. Collier3,
  4. John L. Waddington4,
  5. Jesper Ekelund5,
  6. David J. Porteous6,
  7. Klaus Schughart7 and
  8. Iiris Hovatta8,9
  1. 1Department of Neuroscience and Pharmacology, University Medical Center Utrecht, 3584CG Utrecht, Netherlands.
  2. 2Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, 3584CX Utrecht, Netherlands.
  3. 3Social Genetic and Developmental Psychiatry Centre, Kings College London, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK.
  4. 4Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  5. 5Department of Psychiatry, University of Helsinki, Vaasa Hospital District and Mental Health and Substance Abuse Services, National Institute of Health and Welfare, 00251 Helsinki, Finland.
  6. 6Medical Genetics Section, University of Edinburgh Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.
  7. 7Department of Infection Genetics, Helmholtz Centre for Infection Research and University of Veterinary Medicine Hannover, 38124 Braunschweig, Germany.
  8. 8Research Programs Unit, Molecular Neurology, Biomedicum-Helsinki and Haartman Institute, Department of Medical Genetics, University of Helsinki, 00290 Helsinki, Finland.
  9. 9Mental Health and Substance Abuse Services, National Institute for Health and Welfare, 00300 Helsinki, Finland.
  1. ↵*To whom correspondence should be addressed. E-mail: m.j.h.kas{at}umcutrecht.nl
Science Translational Medicine  28 Sep 2011:
Vol. 3, Issue 102, pp. 102mr3
DOI: 10.1126/scitranslmed.3002917

You are currently viewing the abstract.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution

Free with registration

Abstract

Understanding the etiology of developmental brain disorders such as schizophrenia is critical for achieving advances in treatment and requires new research strategies that control for individual variation in genetic background, environmental challenges, and expression of phenotype. SYSGENET, a European systems genetics network for the study of complex genetic human diseases with mouse genetic reference populations, brought together in Helsinki a cross-disciplinary group of clinical and basic scientists and mouse geneticists to debate, formulate, and prioritize a strategy for future research based on mouse models. The main conclusions of this meeting are summarized here.

View Full Text

Article Tools

  • Email
  • Print
  • Save to my folders
  • Alerts
  • Request Permissions
  • Citation tools

  • Translational Neuroscience of Schizophrenia: Seeking a Meeting of Minds Between Mouse and Man

    By Martien J. Kas, René S. Kahn, David A. Collier, John L. Waddington, Jesper Ekelund, David J. Porteous, Klaus Schughart, Iiris Hovatta

    Science Translational Medicine : 102mr3

    A meeting held 9 June 2011 in Helsinki, Finland, discussed the requirements for creating useful mouse models for schizophrenia.

    Permalink: Copy
    CiteULike logo Connotea logo del.icio.us logo Digg logo Facebook logo Google logo Mendeley logo Reddit logo Twitter logo

Similar Articles in:

Cited By...

Citing Articles in: