Drug Resistance, Epigenetics, and Tumor Cell Heterogeneity

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Science Translational Medicine  21 Apr 2010:
Vol. 2, Issue 28, pp. 28ps19
DOI: 10.1126/scitranslmed.3001056

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The resistance of cancer cells to various therapeutic agents and modalities is a crucial issue in clinical oncology. A recent Cell paper highlights how changes at the chromatin level control drug sensitivity and provides insight into more effective strategies for treating cancer with combination therapies.


  • Citation: T. Hoey, Drug resistance, epigenetics, and tumor cell heterogeneity. Sci. Transl. Med. 2, 28ps19 (2010).

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