PerspectiveInfectious Disease

Fighting Back: Peptidomimetics as a New Weapon in the Battle Against Antibiotic Resistance

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Science Translational Medicine  03 Mar 2010:
Vol. 2, Issue 21, pp. 21ps9
DOI: 10.1126/scitranslmed.3000889

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Abstract

The discovery, development, and clinical exploitation of antibiotics with new mechanisms of action is a top priority in the battle against untreatable infectious diseases. Peptidomimetics can successfully control infections caused by multidrug-resistant pathogens. This Perspective discusses findings in a recent Science paper on a member of this class of therapeutic agents that targets bacterial outer-membrane synthesis.

Footnotes

  • Citation: A. Bragonzi, Fighting back: Peptidomimetics as a new weapon in the battle against antibiotic resistance. Sci. Transl. Med. 2, 21ps9 (2010).

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