Contents

03 February 2010
Vol 2, Issue 17

About The Cover

Cover image expansion

ONLINE COVER A two-fer. This multiplug electrical outlet illustrates the idea behind bi-specific therapeutic proteins discussed by Cochran in this week's Perspective. Bi-specific proteins are engineered to bind two distinct clinical targets, with the goal of achieving enhanced therapeutic effects relative to single-target proteins. These multitasking biologics have begun to enter clinical testing for a variety of biomedical applications. [CREDIT: C. BICKEL/SCIENCE TRANSLATIONAL MEDICINE]