PerspectivePharmacology

“Inactive” ingredients in oral medications

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Science Translational Medicine  13 Mar 2019:
Vol. 11, Issue 483, eaau6753
DOI: 10.1126/scitranslmed.aau6753

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Abstract

Oral forms of medications contain “inactive” ingredients to enhance their physical properties. Using data analytics, we characterized the abundance and complexity of inactive ingredients in approved medications. A majority of medications contain ingredients that could cause adverse reactions, underscoring the need to maximize the tolerability and safety of medications and their inactive ingredients.

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