Research ArticleImaging

Noninvasive high-resolution electromyometrial imaging of uterine contractions in a translational sheep model

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Science Translational Medicine  13 Mar 2019:
Vol. 11, Issue 483, eaau1428
DOI: 10.1126/scitranslmed.aau1428

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Reconstructing contractions

Monitoring uterine contractions during labor is critical to ensure good health of the mother and of the baby. Current methods present several limitations, including low resolution and invasiveness. Now, Wu et al. developed a noninvasive three-dimensional electromyometrial imaging called EMMI, able to monitor uterine contractions with high spatial and temporal resolution. Combining data obtained from electrodes placed on the abdomen with magnetic resonance imaging, EMMI reconstructed uterine contraction patterns in sheep. The results matched reconstructions obtained with invasive electrodes placed on the uterine surface. EMMI might provide an easily accessible method to help doctors during labor and to better understand uterine electrophysiology and pathophysiology.