Editors' ChoiceCancer Immunotherapy

Interfer-ing with immunotherapy-induced autoimmunity

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Science Translational Medicine  09 Jan 2019:
Vol. 11, Issue 474, eaaw0533
DOI: 10.1126/scitranslmed.aaw0533

Abstract

Inhibition of type I IFN prevents autoimmune toxicity while preserving antitumor efficacy of combined cancer vaccine and adoptive cell therapy.

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