Research ArticleBone

Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand

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Science Translational Medicine  07 Nov 2018:
Vol. 10, Issue 466, eaau7137
DOI: 10.1126/scitranslmed.aau7137

Article Information

vol. 10 no. 466

PubMed: 
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History: 
  • Received for publication July 9, 2018
  • Accepted for publication October 15, 2018

Author Information

  1. Julia Luther1,*,
  2. Timur Alexander Yorgan1,*,
  3. Tim Rolvien1,*,
  4. Lorenz Ulsamer1,
  5. Till Koehne1,2,
  6. Nannan Liao1,
  7. Daniela Keller1,,
  8. Nele Vollersen1,
  9. Stefan Teufel1,,
  10. Mona Neven1,
  11. Stephanie Peters1,
  12. Michaela Schweizer3,
  13. Andreas Trumpp4,
  14. Sebastian Rosigkeit5,
  15. Ernesto Bockamp5,
  16. Stefan Mundlos6,7,8,
  17. Uwe Kornak6,7,8,
  18. Ralf Oheim1,
  19. Michael Amling1,§,
  20. Thorsten Schinke1,§ and
  21. Jean-Pierre David1,§
  1. 1Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  2. 2Department of Orthodontics, University Medical Center Hamburg-Eppendorf, D 20246 Hamburg, Germany.
  3. 3Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, D 20251 Hamburg, Germany.
  4. 4Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), D 69120 Heidelberg, Germany.
  5. 5Institute for Translational Immunology and Research Center for Immunotherapy, University Medical Center, Johannes Gutenberg University, D 55131 Mainz, Germany.
  6. 6Institute of Medical Genetics and Human Genetics, Charité-Universitätsmedizin Berlin, D 13353 Berlin, Germany.
  7. 7Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, D 13353 Berlin, Germany.
  8. 8Max Planck Institute for Molecular Genetics, D 14195 Berlin, Germany.
  1. §Corresponding author. Email: j.david{at}uke.de (J.-P.D.); schinke{at}uke.de (T.S.); amling{at}uke.de (M.A.)
    • * These authors contributed equally to this work.

    • Present address: Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, D 13353 Berlin, Germany.

    • Present address: Institute of Experimental Musculoskeletal Medicine, Medical Faculty of the University of Münster, D 48149 Münster, Germany.

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