Research ArticleOsteoarthritis
ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain, and bone
- Frederique M. F. Cornelis1,*,
- Silvia Monteagudo1,*,
- Laura-An K. A. Guns1,
- Wouter den Hollander2,3,
- Rob G. H. H. Nelissen4,
- Lies Storms1,
- Tine Peeters1,
- Ilse Jonkers1,5,
- Ingrid Meulenbelt2,3 and
- Rik J. Lories1,6,†
- 1Laboratory of Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.
- 2Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, Netherlands.
- 3Integrated research on Developmental determinants of Ageing and Longevity (IDEAL), 2300 RC Leiden, Netherlands.
- 4Department of Orthopaedics, Leiden University Medical Center, 2300 RC Leiden, Netherlands.
- 5Human Movement Biomechanics, Department of Kinesiology, KU Leuven, 3000 Leuven, Belgium.
- 6Division of Rheumatology, University Hospitals Leuven, 3000 Leuven, Belgium.
- ↵†Corresponding author. Email: rik.lories{at}kuleuven.be
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Science Translational Medicine 12 Sep 2018:
Vol. 10, Issue 458, eaar8426
DOI: 10.1126/scitranslmed.aar8426