Research ArticleOsteoarthritis

ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain, and bone

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Science Translational Medicine  12 Sep 2018:
Vol. 10, Issue 458, eaar8426
DOI: 10.1126/scitranslmed.aar8426

Article Information

vol. 10 no. 458

Print ISSN: 
Online ISSN: 
  • Received for publication December 22, 2017
  • Resubmitted March 12, 2018
  • Accepted for publication July 31, 2018

Author Information

  1. Frederique M. F. Cornelis1,*,
  2. Silvia Monteagudo1,*,
  3. Laura-An K. A. Guns1,
  4. Wouter den Hollander2,3,
  5. Rob G. H. H. Nelissen4,
  6. Lies Storms1,
  7. Tine Peeters1,
  8. Ilse Jonkers1,5,
  9. Ingrid Meulenbelt2,3 and
  10. Rik J. Lories1,6,
  1. 1Laboratory of Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.
  2. 2Department of Medical Statistics and Bioinformatics, Section Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, Netherlands.
  3. 3Integrated research on Developmental determinants of Ageing and Longevity (IDEAL), 2300 RC Leiden, Netherlands.
  4. 4Department of Orthopaedics, Leiden University Medical Center, 2300 RC Leiden, Netherlands.
  5. 5Human Movement Biomechanics, Department of Kinesiology, KU Leuven, 3000 Leuven, Belgium.
  6. 6Division of Rheumatology, University Hospitals Leuven, 3000 Leuven, Belgium.
  1. Corresponding author. Email: rik.lories{at}
    • * These authors contributed equally to this work as co-first authors.


    Article usage

    Article usage: September 2018 to November 2018

    Sep 20185785595280
    Oct 201868611066
    Nov 20182212929