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A protective Langerhans cell–keratinocyte axis that is dysfunctional in photosensitivity

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Science Translational Medicine  15 Aug 2018:
Vol. 10, Issue 454, eaap9527
DOI: 10.1126/scitranslmed.aap9527

Article Information

vol. 10 no. 454

PubMed: 
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History: 
  • Received for publication September 20, 2017
  • Accepted for publication July 13, 2018

Author Information

  1. William D. Shipman1,2,3,
  2. Susan Chyou3,
  3. Anusha Ramanathan3,
  4. Peter M. Izmirly4,
  5. Sneh Sharma5,6,
  6. Tania Pannellini3,
  7. Dragos C. Dasoveanu3,7,
  8. Xiaoping Qing3,
  9. Cynthia M. Magro8,
  10. Richard D. Granstein9,
  11. Michelle A. Lowes10,
  12. Eric G. Pamer6,
  13. Daniel H. Kaplan11,12,
  14. Jane E. Salmon2,3,13,14,
  15. Babak J. Mehrara15,
  16. James W. Young5,6,10,13,16,
  17. Robert M. Clancy4,
  18. Carl P. Blobel7,13,17,18 and
  19. Theresa T. Lu2,3,14,19,*
  1. 1Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD-PhD Program, New York, NY 10065, USA.
  2. 2Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA.
  3. 3Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, NY 10021, USA.
  4. 4Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
  5. 5Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  6. 6Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  7. 7Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA.
  8. 8Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  9. 9Department of Dermatology, Weill Cornell Medicine, New York, NY 10065, USA.
  10. 10Rockefeller University, New York, NY 10065, USA.
  11. 11Department of Dermatology, University of Pittsburgh, PA 15260, USA.
  12. 12Department of Immunology, University of Pittsburgh, PA 15260, USA.
  13. 13Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  14. 14Division of Rheumatology and Pediatric Rheumatology, Hospital for Special Surgery, New York, NY 10021, USA.
  15. 15Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  16. 16Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  17. 17Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, NY 10021, USA.
  18. 18Institute for Advanced Studies, Technical University Munich, Munich, Germany.
  19. 19Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10065, USA.
  1. *Corresponding author. Email: lut{at}hss.edu

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