Research ArticleBARRIER DYSFUNCTION

The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses

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Science Translational Medicine  06 Jun 2018:
Vol. 10, Issue 444, eaap9736
DOI: 10.1126/scitranslmed.aap9736

Article Information

vol. 10 no. 444

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 15, 2017
  • Resubmitted February 12, 2018
  • Accepted for publication April 27, 2018

Author Information

  1. Nurit P. Azouz1,
  2. Mario A. Ynga-Durand1,2,
  3. Julie M. Caldwell1,
  4. Ayushi Jain1,
  5. Mark Rochman1,
  6. Demetria M. Fischesser3,
  7. Leanne M. Ray1,
  8. Mary C. Bedard1,
  9. Melissa K. Mingler1,
  10. Carmy Forney4,
  11. Matthew Eilerman1,
  12. Jonathan T. Kuhl1,
  13. Hua He5,
  14. Jocelyn M. Biagini Myers6,
  15. Vincent A. Mukkada7,
  16. Philip E. Putnam7,
  17. Gurjit K. Khurana Hershey6,
  18. Leah C. Kottyan4,
  19. Ting Wen1,
  20. Lisa J. Martin5 and
  21. Marc E. Rothenberg1,*
  1. 1Division of Allergy and Immunology, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229–3026, USA.
  2. 2Laboratorio de Inmunidad de Mucosas, Sección de Investigación y Posgrado, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City, Mexico.
  3. 3Division of Molecular Cardiovascular Biology, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229–3026, USA.
  4. 4Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229–3026, USA.
  5. 5Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229–3026, USA.
  6. 6Division of Asthma Research, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229–3026, USA.
  7. 7Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229–3026, USA.
  1. *Corresponding author. Email: rothenberg{at}cchmc.org

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Article usage: June 2018 to October 2018

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Jun 20185901242387
Jul 20184903957
Aug 20185954141
Sep 20182153537
Oct 20181051926