Research ArticleCancer

Development of a stress response therapy targeting aggressive prostate cancer

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Science Translational Medicine  02 May 2018:
Vol. 10, Issue 439, eaar2036
DOI: 10.1126/scitranslmed.aar2036

Article Information

vol. 10 no. 439

Print ISSN: 
Online ISSN: 
  • Received for publication October 12, 2017
  • Resubmitted January 24, 2018
  • Accepted for publication April 6, 2018

Author Information

  1. Hao G. Nguyen1,*,
  2. Crystal S. Conn1,*,,
  3. Yae Kye1,
  4. Lingru Xue1,
  5. Craig M. Forester2,
  6. Janet E. Cowan1,
  7. Andrew C. Hsieh1,,
  8. John T. Cunningham1,§,
  9. Charles Truillet3,
  10. Feven Tameire4,
  11. Michael J. Evans3,
  12. Christopher P. Evans5,
  13. Joy C. Yang5,
  14. Byron Hann6,
  15. Constantinos Koumenis4,
  16. Peter Walter7,
  17. Peter R. Carroll1 and
  18. Davide Ruggero1,8,
  1. 1School of Medicine and Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco, CA 94158, USA.
  2. 2Division of Pediatric Allergy, Immunology and Bone Marrow Transplantation, UCSF, San Francisco, CA 94158, USA.
  3. 3Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA 94158, USA.
  4. 4Department of Radiation Oncology, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  5. 5Department of Urology, University of California Davis School of Medicine, Sacramento, CA 95817, USA.
  6. 6Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, CA 94158, USA.
  7. 7Department of Biochemistry and Biophysics, UCSF, Howard Hughes Medical Institute, San Francisco, CA 94158, USA.
  8. 8Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, CA 94158, USA.
  1. Corresponding author. Email: crystal.conn{at} (C.S.C.); davide.ruggero{at} (D.R.)
    • * These authors contributed equally to this work.

    • Present address: Fred Hutchinson Cancer Research Center and the Department of Medicine, University of Washington, Seattle, WA 98195, USA.

    • § Present address: Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.


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    Article usage: April 2018 to November 2018

    Apr 2018110
    May 201899678701277
    Jun 20181466150192
    Jul 201852471123
    Aug 20182269486
    Sep 20182198778
    Oct 20182428995
    Nov 20181153835