eLetters is an online forum for ongoing peer review. Submission of eLetters are open to all. Please read our Terms of Service before submitting your own eLetter.
Research ArticleDiagnostics
A digital microfluidic system for serological immunoassays in remote settings
- Alphonsus H. C. Ng1,2,*,†,
- Ryan Fobel1,2,*,
- Christian Fobel1,2,*,
- Julian Lamanna1,2,*,
- Darius G. Rackus1,2,*,
- Aimee Summers3,
- Christopher Dixon1,
- Michael D. M. Dryden1,
- Charis Lam1,
- Man Ho1,2,
- Nooman S. Mufti2,4,
- Victor Lee2,
- Mohd Afiq Mohd Asri2,
- Edward A. Sykes1,2,
- M. Dean Chamberlain1,2,
- Rachael Joseph5,
- Maurice Ope5,
- Heather M. Scobie6,
- Alaine Knipes3,
- Paul A. Rota7,
- Nina Marano8,
- Paul M. Chege9,
- Mary Njuguna9,
- Rosemary Nzunza9,
- Ngina Kisangau9,
- John Kiogora10,
- Michael Karuingi10,
- John Wagacha Burton11,
- Peter Borus12,
- Eugene Lam3,‡ and
- Aaron R. Wheeler1,2,4,§
- 1Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.
- 2Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
- 3Division of Global Health Protection, Centers for Disease Control and Prevention, 1600 Clifton Road Northeast, Atlanta, GA 30329, USA.
- 4Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario M5S 3G9, Canada.
- 5Centers for Disease Control and Prevention, Kenya Medical Research Institute (KEMRI) Complex, P.O. Box 606-00621, Mbagathi Road Off Mbagathi Way, Village Market, Nairobi, Kenya.
- 6Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
- 7Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
- 8Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
- 9Kenya Field Epidemiology and Laboratory Training Program, Ministry of Health, P.O. Box 30016–00100, Afya House, Cathedral Road, Nairobi, Kenya.
- 10International Rescue Committee, P.O. Box 62727, Galana Plaza, 4th Floor Galana Road, Kilimani, Nairobi, Kenya.
- 11Office of the United Nations High Commissioner for Refugees, P.O. Box 43801-00100, Lynwood Court, Off Waiyaki Way, Westland, Nairobi, Kenya.
- 12KEMRI, P.O. Box 54840-00200, Off Mbagathi Road, Nairobi, Kenya.
- ↵§Corresponding author. Email: aaron.wheeler{at}utoronto.ca
↵* These authors contributed equally to this work.
↵† Present address: Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA.
↵‡ Present address: Division of Health Emergencies and Communicable Diseases, World Health Organization Regional Office for Europe, UN City, Marmorvej 51, DK-2100 Copenhagen Ø, Denmark.
See allHide authors and affiliations
Science Translational Medicine 25 Apr 2018:
Vol. 10, Issue 438, eaar6076
DOI: 10.1126/scitranslmed.aar6076
Vol. 10, Issue 438, eaar6076
DOI: 10.1126/scitranslmed.aar6076
Alphonsus H. C. Ng
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
Ryan Fobel
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
Christian Fobel
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
Julian Lamanna
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
Darius G. Rackus
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
Aimee Summers
Division of Global Health Protection, Centers for Disease Control and Prevention, 1600 Clifton Road Northeast, Atlanta, GA 30329, USA.
Christopher Dixon
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.
Michael D. M. Dryden
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.
Charis Lam
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.
Man Ho
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
Nooman S. Mufti
Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario M5S 3G9, Canada.
Victor Lee
Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
Mohd Afiq Mohd Asri
Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
Edward A. Sykes
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
M. Dean Chamberlain
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
Rachael Joseph
Centers for Disease Control and Prevention, Kenya Medical Research Institute (KEMRI) Complex, P.O. Box 606-00621, Mbagathi Road Off Mbagathi Way, Village Market, Nairobi, Kenya.
Maurice Ope
Centers for Disease Control and Prevention, Kenya Medical Research Institute (KEMRI) Complex, P.O. Box 606-00621, Mbagathi Road Off Mbagathi Way, Village Market, Nairobi, Kenya.
Heather M. Scobie
Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Alaine Knipes
Division of Global Health Protection, Centers for Disease Control and Prevention, 1600 Clifton Road Northeast, Atlanta, GA 30329, USA.
Paul A. Rota
Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Nina Marano
Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Paul M. Chege
Kenya Field Epidemiology and Laboratory Training Program, Ministry of Health, P.O. Box 30016–00100, Afya House, Cathedral Road, Nairobi, Kenya.
Mary Njuguna
Kenya Field Epidemiology and Laboratory Training Program, Ministry of Health, P.O. Box 30016–00100, Afya House, Cathedral Road, Nairobi, Kenya.
Rosemary Nzunza
Kenya Field Epidemiology and Laboratory Training Program, Ministry of Health, P.O. Box 30016–00100, Afya House, Cathedral Road, Nairobi, Kenya.
Ngina Kisangau
Kenya Field Epidemiology and Laboratory Training Program, Ministry of Health, P.O. Box 30016–00100, Afya House, Cathedral Road, Nairobi, Kenya.
John Kiogora
International Rescue Committee, P.O. Box 62727, Galana Plaza, 4th Floor Galana Road, Kilimani, Nairobi, Kenya.
Michael Karuingi
International Rescue Committee, P.O. Box 62727, Galana Plaza, 4th Floor Galana Road, Kilimani, Nairobi, Kenya.
John Wagacha Burton
Office of the United Nations High Commissioner for Refugees, P.O. Box 43801-00100, Lynwood Court, Off Waiyaki Way, Westland, Nairobi, Kenya.
Peter Borus
KEMRI, P.O. Box 54840-00200, Off Mbagathi Road, Nairobi, Kenya.
Eugene Lam
Division of Global Health Protection, Centers for Disease Control and Prevention, 1600 Clifton Road Northeast, Atlanta, GA 30329, USA.
Aaron R. Wheeler
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario M5S 3G9, Canada.
Submit a Response to This Article
No eLetters have been published for this article.