Research ArticleCancer

Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer

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Science Translational Medicine  11 Apr 2018:
Vol. 10, Issue 436, eaao5931
DOI: 10.1126/scitranslmed.aao5931

Article Information

vol. 10 no. 436

Print ISSN: 
Online ISSN: 
  • Received for publication August 6, 2017
  • Accepted for publication February 19, 2018

Author Information

  1. Janos L. Tanyi1,*,
  2. Sara Bobisse2,*,
  3. Eran Ophir2,*,
  4. Sandra Tuyaerts2,
  5. Annalisa Roberti1,
  6. Raphael Genolet2,
  7. Petra Baumgartner2,
  8. Brian J. Stevenson3,
  9. Christian Iseli3,
  10. Denarda Dangaj2,
  11. Brian Czerniecki4,
  12. Aikaterini Semilietof2,
  13. Julien Racle2,3,
  14. Alexandra Michel2,
  15. Ioannis Xenarios3,
  16. Cheryl Chiang1,
  17. Dimitri S. Monos5,
  18. Drew A. Torigian6,
  19. Harvey L. Nisenbaum6,
  20. Olivier Michielin2,3,
  21. Carl H. June7,
  22. Bruce L. Levine7,
  23. Daniel J. Powell Jr.1,
  24. David Gfeller2,3,
  25. Rosemarie Mick8,
  26. Urania Dafni9,
  27. Vincent Zoete2,3,
  28. Alexandre Harari2,,
  29. George Coukos1,2, and
  30. Lana E. Kandalaft1,2,,
  1. 1Ovarian Cancer Research Center, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  2. 2Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland.
  3. 3Swiss Institute of Bioinformatics, Lausanne CH-1015, Switzerland.
  4. 4Department of Breast Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
  5. 5Immunogenetics Laboratory, Department of Pathology and Laboratory Medicine, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  6. 6Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
  7. 7Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA 19104, USA.
  8. 8Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  9. 9Laboratory of Biostatistics, School of Health Sciences, National and Kapodistrian, University of Athens, Athens, Greece.
  1. Corresponding author. Email: lana.kandalaft{at}
    • * These authors contributed equally to this work.

    • These authors provided equal supervision to this work.


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