Research ArticleRetinal Disease

A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration

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Science Translational Medicine  04 Apr 2018:
Vol. 10, Issue 435, eaao4097
DOI: 10.1126/scitranslmed.aao4097

Article Information

vol. 10 no. 435

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 26, 2017
  • Resubmitted September 28, 2017
  • Accepted for publication March 23, 2018

Author Information

  1. Amir H. Kashani1,*,
  2. Jane S. Lebkowski2,
  3. Firas M. Rahhal3,
  4. Robert L. Avery4,
  5. Hani Salehi-Had5,
  6. Wei Dang6,
  7. Chih-Min Lin6,
  8. Debbie Mitra1,
  9. Danhong Zhu7,
  10. Biju B. Thomas1,
  11. Sherry T. Hikita8,
  12. Britney O. Pennington8,
  13. Lincoln V. Johnson2,8,
  14. Dennis O. Clegg8,
  15. David R. Hinton1,7 and
  16. Mark S. Humayun1,9,*
  1. 1University of Southern California (USC) Roski Eye Institute, USC Institute for Biomedical Therapeutics, and Department of Ophthalmology, Keck School of Medicine, USC, 1450 San Pablo, Los Angeles, CA 90033, USA.
  2. 2Regenerative Patch Technologies, 150 Gabarda Way, Portola Valley, CA 94028–7445, USA.
  3. 3Retina Vitreous Associates Medical Group, 9001 Wilshire Boulevard, Suite 301, Beverly Hills, CA 90211, USA.
  4. 4California Retina Consultants, 525 East Micheltorena Street, Santa Barbara, CA 93103, USA.
  5. 5Atlantis Eyecare, 7777 Edinger Avenue, Suite 234, Huntington Beach, CA 92647, USA.
  6. 6Center for Biomedicine and Genetics, Beckman Research Institute of City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA.
  7. 7Department of Pathology, Keck School of Medicine, USC, 1441 Eastlake Avenue, NRT 7503, Los Angeles, CA 90033, USA.
  8. 8Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, Mail Code 5060, University of California, Santa Barbara, CA 93016, USA.
  9. 9Department of Biomedical Engineering, 1042 Downey Way, Denney Research Center (DRB) 140, USC, Los Angeles, CA 90089–1111, USA.
  1. *Corresponding author. Email: humayun{at}usc.edu (M.S.H.); ahkashan{at}usc.edu (A.H.K.)

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Apr 201816348590971
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Jun 20188043864