Editors' ChoiceAutoimmunity

Double safety reins in wayward B cells

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Science Translational Medicine  28 Mar 2018:
Vol. 10, Issue 434, eaat3886
DOI: 10.1126/scitranslmed.aat3886

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Abstract

Two regulatory proteins suppress IRF5 transcription factor in age-associated B cells to prevent systemic autoimmune disorders.

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