Editors' ChoiceInfectious Disease

No one is naïve: Young infant’s immunity can dodge Darwinian selection

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Science Translational Medicine  07 Feb 2018:
Vol. 10, Issue 427, eaar7530
DOI: 10.1126/scitranslmed.aar7530

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Abstract

Unlike adults, young infant antibody responses against respiratory syncytial virus are biased toward limited antigenic sites, suggesting a blueprint for future infant and age-specific vaccines.

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