Editors' ChoiceCancer

Deadly role of chromosomal instability in metastasis

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Science Translational Medicine  07 Feb 2018:
Vol. 10, Issue 427, eaar7528
DOI: 10.1126/scitranslmed.aar7528

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Abstract

Chromosomal instability produces cytosolic micronuclei that rupture and activate a viral response pathway, driving metastasis.

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