PerspectiveBIOMATERIALS

Engineering precision biomaterials for personalized medicine

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Science Translational Medicine  17 Jan 2018:
Vol. 10, Issue 424, eaam8645
DOI: 10.1126/scitranslmed.aam8645

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Abstract

As the demand for precision medicine continues to rise, the “one-size-fits-all” approach to designing medical devices and therapies is becoming increasingly outdated. Biomaterials have considerable potential for transforming precision medicine, but individual patient complexity often necessitates integrating multiple functions into a single device to successfully tailor personalized therapies. Here, we introduce an engineering strategy based on unit operations to provide a unified vocabulary and contextual framework to aid the design of biomaterial-based devices and accelerate their translation.

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