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Mechanobiologically optimized 3D titanium-mesh scaffolds enhance bone regeneration in critical segmental defects in sheep

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Science Translational Medicine  10 Jan 2018:
Vol. 10, Issue 423, eaam8828
DOI: 10.1126/scitranslmed.aam8828

Article Information

vol. 10 no. 423

PubMed: 
Print ISSN: 
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History: 
  • Received for publication January 31, 2017
  • Resubmitted July 21, 2017
  • Accepted for publication November 28, 2017

Author Information

  1. Anne-Marie Pobloth1,
  2. Sara Checa1,
  3. Hajar Razi1,2,
  4. Ansgar Petersen1,3,
  5. James C. Weaver4,
  6. Katharina Schmidt-Bleek1,
  7. Markus Windolf5,
  8. Andras Á. Tatai6,
  9. Claudia P. Roth1,
  10. Klaus-Dieter Schaser6,7,
  11. Georg N. Duda1,3,*, and
  12. Philipp Schwabe6,
  1. 1Julius Wolff Institute, Charité–Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
  2. 2Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany.
  3. 3Berlin-Brandenburg Center for Regenerative Therapies, Charité–Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
  4. 4Wyss Institute, Center for Life Science Building, 3 Blackfan Circle, Boston, MA 02115, USA.
  5. 5AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos, Switzerland.
  6. 6Center for Musculoskeletal Surgery, Charité–Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
  7. 7Department of Orthopaedic and Trauma Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
  1. *Corresponding author. Email: georg.duda{at}charite.de
    • These authors contributed equally to this work.

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