Research ArticleTINNITUS
Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans
- Kendra L. Marks1,*,
- David T. Martel1,2,*,
- Calvin Wu1,*,
- Gregory J. Basura1,
- Larry E. Roberts3,
- Kara C. Schvartz-Leyzac1 and
- Susan E. Shore1,2,4,†
- 1Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109, USA.
- 2Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
- 3Department of Psychology, Neuroscience and Behavior McMaster University, Hamilton, Ontario, Canada.
- 4Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
- ↵†Corresponding author. Email: sushore{at}umich.edu
↵* These authors contributed equally to this work.
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Science Translational Medicine 03 Jan 2018:
Vol. 10, Issue 422, eaal3175
DOI: 10.1126/scitranslmed.aal3175
Vol. 10, Issue 422, eaal3175
DOI: 10.1126/scitranslmed.aal3175
Kendra L. Marks
Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109, USA.
David T. Martel
Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109, USA.Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Calvin Wu
Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109, USA.
Gregory J. Basura
Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109, USA.
Larry E. Roberts
Department of Psychology, Neuroscience and Behavior McMaster University, Hamilton, Ontario, Canada.
Kara C. Schvartz-Leyzac
Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109, USA.
Susan E. Shore
Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109, USA.Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.