Editors' ChoiceCancer and Inflammation

Cancer Transformers

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Science Translational Medicine  04 Nov 2009:
Vol. 1, Issue 5, pp. 5ec18
DOI: 10.1126/scitranslmed.3000547

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Summary

Environmental factors such as inflammation can trip an epigenetic switch that causes self-propelling cancer progression, without mutations in tumor suppressor genes or oncogenes.