Editors' ChoiceLung Disease

A Protective Genetic Variant for Lungs

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Science Translational Medicine  23 Dec 2009:
Vol. 1, Issue 12, pp. 12ec43
DOI: 10.1126/scitranslmed.3000732

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Analysis of seven independent groups of subjects uncovers a metalloproteinase variant that protects against lung damage—but only in smokers and people with lung disease.